FERMT1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52109
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | C20orf42,Chromosome 20 open reading frame 42,DTGCU 2,DTGCU2,FERM1,Fermitin family homolog 1,Fermitin family member 1,Fermt1,FLJ20116,FLJ23423,KIND 1,KIND1,Kinderlin,Kindlerin,Kindlin 1,Kindlin syndrome protein,Kindlin-1,Kindlin1,Unc 112 related protein 1,Unc-112-related protein 1,Unc112 related protein ,UNC112A,URP 1,URP1,FERMT1抗体 |
| Swissprot | Q9BQL6 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human FERMT1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:100 |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm>cytoskeleton. Cell junction>focal adhesion. Cell projection>ruffle membrane. Constituent of focal adhesions. Localized at the basal aspect of skin keratinocytes, close to the cell membrane. Colocalizes with filamentous actin. Upon TGFB1 treatment, it localizes to membrane ruffles. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of the fermitin family, and contains a FERM domain and a pleckstrin homology domain. The encoded protein is involved in integrin signaling and linkage of the actin cytoskeleton to the extracellular matrix. Mutations in this gene have been linked to Kindler syndrome. |
