FHL1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15036
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | bA535K18.1,FHL 1,FHL 1B,FHL-1,FHL1,FHL1 protein,FHL1,FHL1A,FHL1B,FLH1A,Four and a half LIM domains 1,Four and a half LIM domains protein 1,Four and a half Lin11 Isl 1 and Mec 3 domains 1,four-and-a-half Lin11,Isl-1 and Mec-3,KYO T,KYOT,mouse,homolog of,LIM protein SLIMMER,MGC111107,RAM14-1,RBMX1A,RBMX1B,RBP associated molecule 14-1,RP11-535K18.1,Skeletal muscle LIM protein 1,Skeletal muscle LIM-protein 1,SLIM 1,SLIM,SLIM-1,SLIM1,SLIMMER,XMPMA,FHL1抗体 |
| Swissprot | Q13642 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human FHL1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm; Cytoplasm. Nucleus and Nucleus. Cytoplasm>cytosol. Predominantly nuclear in myoblasts but is cytosolic in differentiated myotubes. |
| Tissue specificity | Isoform 1 is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. Expression is barely detectable in brain, lung, liver, kidney, pancreas, thymus and peripheral blood leukocytes. Isoform 2 is expressed in brain, skeletal muscle and to a lesser extent in heart, colon, prostate and small intestine. Isoform 3 is expressed in testis, heart and skeletal muscle. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described. |
Images
Western Blot analysis of Human adrenal pheochromocytoma, fetal muscle and skeletal muscle tissue using FHL1 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human colon cancer using FHL1 Polyclonal Antibody at dilution of 1:20
Immunohistochemistry of paraffin-embedded Human liver cancer using FHL1 Polyclonal Antibody at dilution of 1:20
