FKBP4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19050
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | 51 kDa FK506-binding protein,52 kDa FK506 binding protein,52 kDa FK506-binding protein,52 kDa FKBP,59 kDa immunophilin,FK506 binding protein 4,FK506-binding protein 4,FKBP 4,FKBP 52,FKBP 59,FKBP-4,FKBP-52,FKBP4,FKBP4,FKBP51,FKBP52 protein,FKBP59,HBI,Hsp 56,HSP binding immunophilin,HSP-binding immunophilin,Hsp56,Immunophilin FKBP52,N-terminally processed,p52,p59,p59 protein,Peptidyl prolyl cis trans isomerase,Peptidyl-prolyl cis-trans isomerase FKBP4,Peptidylprolyl cis trans isomerase,PPIase,PPIase FKBP4,Rotamase,T cell FK506 binding protein 59kD,FKBP4抗体 |
| Swissprot | Q02790 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human FKBP4 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:300; |
| Concentration | 1.14mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm>cytosol. Nucleus. Cytoplasm>cytoskeleton. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia. |
