FLK1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70080
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | CD309,CD309 antigen,EC 2.7.10.1,Fetal liver kinase 1,FLK-1,FLK1,FLK1,mouse,homolog of,Kdr,Kinase insert domain receptor (a type III receptor tyrosine kinase),Kinase insert domain receptor,KRD1,Ly73,Protein tyrosine kinase receptor FLK1,Protein-tyrosine kinase receptor flk-1,soluble VEGFR2,Tyrosine kinase growth factor receptor,Vascular endothelial growth factor receptor 2,VEGFR 2,VEGFR,VEGFR-2,VEGFR2,VGFR2,FLK1抗体 |
| Swissprot | P35968,P35918,O08775 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse VEGFR2 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:1000; |
| Concentration | 1.1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Detected in cornea (at protein level). Widely expressed.Highest expression level in lung. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. |
