FOLR1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19878
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | adult,Adult folate binding protein,Adult folate-binding protein,FBP,Folate Receptor 1 Adult,Folate receptor 1,Folate Receptor 1 Precursor,Folate receptor adult,Folate receptor alpha,Folate receptor,FOLR,FOLR1,FOLR1,FR alpha,FR-alpha,FRalpha,KB cells FBP,MOV18,Ovarian cancer associated antigen,Ovarian tumor associated antigen,Ovarian tumor associated antigen MOv18,Ovarian tumor-associated antigen MOv18,FOLR1抗体 |
| Swissprot | P15328 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human FOLR1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:200 |
| Concentration | 2.28mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Secreted. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Folate receptor 1 (FOLR1),also known as folate receptor alpha or adult folate-binding protein (FBP),is a 38-kDa glycoprotein belonging to the folate receptor family . The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung,kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer,non-small cell lung cancer,breast cancer,kidney cancer and high-grade osteosarcoma . |
