FTO Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11248
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | AlkB homolog 9,ALKBH9,Alpha-ketoglutarate-dependent dioxygenase FTO,AW743446,Fat mass and obesity-associated protein,FATSO,MOUSE,HOMOLOG OF,Fto,FTO,GDFD,KIAA1752,mKIAA1752,Protein fatso,FTO抗体 |
| Swissprot | Q9C0B1 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human FTO |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300; |
| Concentration | 0.7 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Tissue specificity | Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. |
Images
Western Blot analysis of Human fetal brain tissue using FTO Polyclonal Antibody at dilution of 1:650
Immunohistochemistry of paraffin-embedded Human breast cancer using FTO Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human esophagus cancer using FTO Polyclonal Antibody at dilution of 1:60
