GABAA Receptor alpha1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70290
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | ECA4,EIEE19,EJM,EJM5,Gaba receptor alpha 1 polypeptide,GABA(A) receptor,GABA(A) receptor subunit alpha 1,GABA(A) receptor subunit alpha-1,GABA(A) receptor,alpha 1,GABRA 1,GABRA1,Gamma aminobutyric acid (GABA) A receptor alpha 1,Gamma aminobutyric acid A receptor alpha 1,Gamma aminobutyric acid receptor subunit alpha 1,Gamma aminobutyric acid type A receptor alpha1 subunit,Gamma-aminobutyric acid receptor subunit alpha-1,GBRA1,GABAA Receptor alpha1抗体 |
| Swissprot | P14867,P62813,P62812 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to mouse GABA A Receptor alpha 1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.73 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell junction, Cell membrane, Cytoplasmic vesicle, Membrane, Postsynaptic cell membrane, Synapse |
| Tissue specificity | Highest expression level in dorsolateral prefrontal cortex |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene |
