Galectin 3 Polyclonal Antibody
| 规格： | / 50μL / 100μL |
| 价格： | / ￥1010 / ￥1640 |
货号：D-AB-10120L
货期：咨询
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | 35 kDa lectin,Carbohydrate binding protein 35,Carbohydrate-binding protein 35,CBP 35,CBP35,Gal-3,GAL3,Galactose-specific lectin 3,Galactoside-binding protein,GALBP,Galectin 3 internal gene,included,Galectin-3,Galectin3,GALIG,GBP,IgE binding protein,IgE-binding protein,L 31,L 34,L-31,L-34 galactoside-binding lectin,L31,Laminin-binding protein,Lectin L-29,Lectin,galactose binding,soluble 3,LEG3,LGALS2,LGALS3,MAC 2 antigen,Mac-2,Mac-2 antigen,MAC2,Macrophage galactose-specific lectin,MGC105387 |
| Swissprot | P17931 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant Human LGALS3 protein expressed by E.coli |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:150-1:300; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm, Nucleus, Secreted, Spliceosome |
| Tissue specificity | A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes. |
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides . Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell,being present on the cell surface or in the extracellular space . Galectin-3 is involved in various biological processes including cell growth,adhesion,differentiation,apoptosis,angiogenesis,immune response,neoplastic transformation and metastasis . |
Images
Western Blot analysis of 1)MCF-7, 2)NIH/3T3, 3)Raw264.7 using Galectin 3 Ployclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human colon cancer using LGALS3 Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human stomach cancer using LGALS3 Polyclonal Antibody at dilution of 1:300
