Galectin 3 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70106
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | 35 kDa lectin,Carbohydrate binding protein 35,Carbohydrate-binding protein 35,CBP 35,CBP35,Gal-3,GAL3,Galactose-specific lectin 3,Galactoside-binding protein,GALBP,Galectin 3 internal gene,included,Galectin-3,Galectin3,GALIG,GBP,IgE binding protein,IgE-binding protein,L 31,L 34,L-31,L-34 galactoside-binding lectin,L31,Laminin-binding protein,Lectin L-29,Lectin,galactose binding,soluble 3,LEG3,LGALS2,LGALS3,MAC 2 antigen,Mac-2,Mac-2 antigen,MAC2,Macrophage galactose-specific lectin,MGC105387,Galectin 3抗体 |
| Swissprot | P17931,P08699,P16110 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein corresponding to Mouse Mac2 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 370 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasmic in adenomas and carcinomas. May be secreted by a non-classical secretory pathway and associate with the cell surface. |
| Tissue specificity | A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes.Highest expression level in colonic mucosa. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides . Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell,being present on the cell surface or in the extracellular space . Galectin-3 is involved in various biological processes including cell growth,adhesion,differentiation,apoptosis,angiogenesis,immune response,neoplastic transformation and metastasis . |
