GBA Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19899
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | Acid beta glucosidase,Acid beta-glucosidase,Alglucerase,Beta glucocerebrosidase,BETA GLUCOSIDASE, ACID,Beta-glucocerebrosidase,betaGC,D glucosyl N acylsphingosine glucohydrolase,D-glucosyl-N-acylsphingosine glucohydrolase,EC 3.2.1.45 ,GBA,Gba protein ,GBA1,GC,GCase,GCB,GLCM,GLUC,Glucocerebrosidase (alt.) ,Glucocerebrosidase,GLUCOCEREBROSIDASE PSEUDOGENE,Glucosidase beta,Glucosidase, beta, acid,Glucosidase, beta; acid (includes glucosylceramidase),Glucosylceramidase,Imiglucerase,Lysosomal glucocerebrosidase ,OTTHUMP00000033992,OTTHUMP00000033993,GBA抗体 |
| Swissprot | P04062 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human GBA |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:100; |
| Concentration | 1.56mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Lysosome membrane. Interaction with saposin-C promotes membrane association. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. |
Images
Western blot analysis of 231 cell lysate using GBA Polyclonal Antibody at dilution of 1:1350
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using GBA Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using GBA Polyclonal Antibody at dilution of 1:55(×200)
