GCKR Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-13267
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | FGQTL5,GCK,GCKR,GCKR,GKRP,GLRE,glucokinase (hexokinase 4) regulator,Glucokinase,Glucokinase regulator,Glucokinase regulatory protein,Hexokinase 4 regulator,Hexokinase type IV,Hexokinase-4,Hexokinase-D,HK IV,HK4,OTTHUMP00000158533,GCKR抗体 |
| Swissprot | Q14397 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human GCKR |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300; |
| Concentration | 0.9 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Nucleus,nucleoplasm,Other locations:cytoplasm |
| Tissue specificity | Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). |
