GFRA1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53255
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | GDNF family receptor alpha 1,GDNF family receptor alpha-1,GDNF R,GDNF RA,GDNF receptor alpha,GDNF receptor alpha-1,GDNFR alpha 1,GDNFR alpha,GDNFR,GDNFR-alpha-1,GDNFRA,GDNFRalpha,GFR alpha 1,GFR alpha1,GFR-alpha-1,GFRA 1,Gfra1,GFRA1,GFRalpha1,Glial cell line derived neurotrophic factor receptor alpha,GPI linked anchor protein,MGC23045,PI linked cell surface accessory protein,RET 1L,RET ligand 1,RET1L,RETL 1,RETL1,TGF beta related neurotrophic factor receptor 1,TGF-beta-related neurotrophic factor receptor 1,TRNR 1,TRNR1,GFRA1抗体 |
| Swissprot | P56159 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human GFRA1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 1.92mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. |
Images
Western blot analysis of Rat brain tissue lysate using GFRA1 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human brain tissue using GFRA1 Polyclonal Antibody at dilution of 1:65(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using GFRA1 Polyclonal Antibody at dilution of 1:65(×200)
