GFRA2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53256
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | GDNF family receptor alpha 2,GDNF family receptor alpha-2,GDNF receptor alpha-2,GDNF receptor beta,GDNFR beta,GDNFR-alpha-2,GDNFR-beta,GDNFRB,GFR alpha 2,GFR-alpha-2,GFRA 2,Gfra2,GFRA2,Glial cell line derived neurotrophic factor family receptor alpha2b,Glial cell line derived neurotrophic factor receptor beta,Neurturin receptor alpha,NRTNR alpha,NRTNR-alpha,NTNR alpha,NTNR-alpha,NTNRA,PI linked cell surface accessory protein,PI linked cell-surface accessory protein,RET ligand 2,RETL 2,RETL2,TGF beta related neurotrophic factor receptor 2,TGF-beta-related neurotrophic factor receptor 2,TRN receptor GPI anchored,TRNR 2,TRNR2,GFRA2抗体 |
| Swissprot | O00451 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human GFRA2 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000 |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. |
