GIPR Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3580 |
货号:E-AB-62759
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
Synonyms | GIPR,PGQTL2,GIPR抗体 |
Swissprot | P48546 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant fusion protein of human GIPR (NP_000155.1). |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,, 1:500-1:2000; |
Concentration | 1 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20°C. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Background | This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. |