GLIPR1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15071
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | CRISP 7,CRISP7,GLI pathogenesis related 1,GLI pathogenesis-related 1 (glioma),Glioma pathogenesis related protein 1,Glioma pathogenesis-related protein 1,GLIP1,GliPR 1,GLIPR,GLIPR1,Protein RTVP-1,RELATED TO TESTIS SPECIFIC,VESPID,AND PATHOGENESIS PROTEINS 1,RTVP 1,RTVP1,Testes specific vespid and pathogenesis protein 1,testes-specific vespid and pathogenesis protein 1,GLIPR1抗体 |
| Swissprot | P48060 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human GLIPR1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | According to PubMed:8973356, it is ubiquitously expressed with high levels in lung and kidney and low levels in heart and liver. Highly expressed in cell lines derived from nervous system tumors arising from glia, low or absent in non-glial-derived nervous system tumor cell lines. Also found in fetal kidney. According to PubMed:7607567 it is expressed only in brain tumor glioblastoma multiforme/astrocytoma and not in other nervous system tumors or normal fetal or adult tissues. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
