GLP1R Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3580 |
货号：E-AB-62762
宿主: Rabbit
反应性: M,R
应用: WB
Overview
| Synonyms | GLP1R,GLP-1,GLP-1-R,GLP-1R,GLP1R抗体 |
| Swissprot | P43220 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | Recombinant fusion protein of human GLP1R (NP_002053.3). |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,, 1:500-1:2000; |
| Concentration | 1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20°C. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Background | This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. |
