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GLUT-3 Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3300

货号:E-AB-70154

宿主: Rabbit

反应性: H,R

应用: WB,IHC

  • 详情
  • Overview

    Synonyms brain,FLJ90380,Glucose transporter type 3,Glucose transporter type 3 brain,GLUT 3,GLUT-3,GLUT3,GTR3,Slc2a3,Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3,Solute carrier family 2,facilitated glucose transporter member 3,GLUT-3抗体
    Swissprot P11169,P32037,Q07647
    Source Rabbit
    Reactivity Human,Rat
    Immunogen KLH conjugated Synthetic peptide corresponding to Mouse GLUT3
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:1000;IHC,,1:200-1:800;
    Concentration 360 μg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Membrane.
    Tissue specificity Highly expressed in brain. Expressed in many tissues.Highest expression level in embryo.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background Glucose transporter 3 (or GLUT3), also known as solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3) is a protein that in humans is encoded by the SLC2A3 gene. GLUT3 facilitates the transport ofglucose across the plasma membranes of mammalian cells. GLUT3 is most known for its specific expression in neurons and has originally been designated as the neuronal GLUT. GLUT3 has been studied in other cell types with specific glucose requirements, including sperm, preimplantation embryos, circulating white blood cells and carcinoma cell lines. GLUT3 has both a higher affinity for glucose and at least a fivefold greater transport capacity than GLUT1, GLUT2 and GLUT4, which is particularly significant for its role in neuronal glucose transport, where ambient glucose levels are fivefold lower than in serum.
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