GNA13 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14089
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | G alpha 13,G alpha-13,G-protein subunit alpha-13,GNA13,GNA13,Guanine nucleotide binding protein (G protein) alpha 13,Guanine nucleotide binding protein alpha 13 subunit,Guanine nucleotide-binding protein subunit alpha-13,GNA13抗体 |
| Swissprot | Q14344 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human GNA13 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Tissue specificity | Expressed in testis, including in Leydig cells and in the seminiferous epithelium, in differentiating cells from the spermatogonia to mature spermatozoa stages and round spermatids (at protein level). Expressed in 99.2% of spermatozoa from healthy individuals, but only in 28.6% of macrocephalic spermatozoa from infertile patients (at protein level). |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Guanine nucleotide-binding protein subunit alpha-13 is aproteinthat in humans is encoded by the GNA13 gene. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5. Interacts with HAX1. Interacts (when active) with PPP5C (via TPR repeats); activates PPP5C phosphatase activity and translocates PPP5C to the cell membrane. |
Images
Western Blot analysis of Mouse kidney tissue, Human testis and brain malignant glioma tissue using GNA13 Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human tonsil using GNA13 Polyclonal Antibody at dilution of 1:20
Immunohistochemistry of paraffin-embedded Human brain using GNA13 Polyclonal Antibody at dilution of 1:20
