GNAI1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19249
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Adenylate cyclase inhibiting G alpha protein,Adenylate cyclase inhibitory protein,Adenylate cyclase-inhibiting G alpha protein,G protein alpha inhibiting 1,G protein alpha inhibiting activity polypeptide 1,Gi,Gi inhibitory G protein,Gi1 protein alpha subunit,GNAI 1,GNAI1,GNAI1,Guanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 1,Guanine nucleotide binding protein alpha inhibiting activity polypeptide 1,Guanine nucleotide binding protein G(i) alpha 1 subunit,Guanine nucleotide-binding protein G(i) subunit alpha-1,OTTHUMP00000161319,OTTHUMP00000208047,GNAI1抗体 |
| Swissprot | P63096 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human GNAI1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:200 |
| Concentration | 2.1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm. Cell membrane. Cytoplasm>cytoskeleton>centrosome. Localized at the plasma membrane throughout mitosis. Colocalizes with RIC8A and RGS14 at the plasma membrane (By similarity). Localizes in the centrosomes of interphase and mitotic cells, but not in centrosomes during cytokinesis. Detected at the cleavage furrow or the midbody. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase. Two transcript variants encoding different isoforms have been found for this gene. |
