GNAT1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18009
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | CSNBAD3,GBT1,GNAT1,GNAT1,GNATR,guanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 1,guanine nucleotide binding protein G(T) alpha 1 subunit,Guanine nucleotide-binding protein G(t) subunit alpha-1,Rod specific transducin,rod-type transducin alpha subunit,Transducin alpha-1 chain,transducin,rod-specific,GNAT1抗体 |
| Swissprot | P11488 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human GNAT1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
| Concentration | 0.72mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Plasma Membrane,apical plasma membrane,heterotrimeric G-protein complex,photoreceptor disc membrane,photoreceptor outer segment membrane,plasma membrane,Other locations:membrane,neuronal cell body,photoreceptor connecting cilium,photoreceptor inner segment,photoreceptor outer segment |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.GNAT1 (G Protein Subunit Alpha Transducin 1) is a Protein Coding gene. Diseases associated with GNAT1 include Night Blindness, Congenital Stationary, Autosomal Dominant 3 and Night Blindness, Congenital Stationary, Type 1G. Among its related pathways are Phospholipase-C Pathway and Phototransduction. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is GNAT2. |
