GOT1 Polyclonal Antibody
| 规格： | / 20μL / 50μL / 100μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40505
宿主: Rabbit
反应性: Z
应用: WB
Overview
| Synonyms | AATC,Aspartate aminotransferase 1,Aspartate aminotransferase,Aspartate aminotransferase cytoplasmic,Aspartate aminotransferase cytosolic,ASTQTL1,cAspAT,cCAT,cysteine aminotransferase,cytoplasmic,cysteine transaminase,cytoplasmic,cytoplasmic,ec 2.6.1.1,GIG 18,GIG18,Glutamate oxaloacetate transaminase 1,Glutamate oxaloacetate transaminase soluble,Glutamic oxaloacetic transaminase 1 soluble,GOT 1,GOT1,Growth inhibiting protein 18,SGOT,Transaminase A |
| Swissprot | P17174 |
| Source | Rabbit |
| Reactivity | Zebrafish |
| Immunogen | Recombinant human GOT1 protein expressed by E.coli |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:1000-2000; |
| Concentration | 15mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm |
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or serum glutamic oxaloacetic transaminase (SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme. Low levels of AST are normally found in the blood. Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. In addition, catalyzes (2S)-2-aminobutanoate, a by-product in the cysteine biosynthesis pathway. |
