GPC3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53438
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | DGSX,Glypican proteoglycan 3,Glypican-3 [Precursor],Gpc3,GPC3,GTR2 2,GTR2-2,Heparan sulphate proteoglycan,Intestinal protein OCI 5,Intestinal protein OCI-5,MXR7,OCI 5,OCI-5,OCI5,SDYS,Secreted glypican-3,SGB,SGBS,SGBS1,GPC3抗体 |
| Swissprot | P51654 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human GPC3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:200 |
| Concentration | 1.8mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane and Secreted>extracellular space. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. |
