GPM6A Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14718
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | GPM6A,GPM6A,M6a,Neuronal membrane glycoprotein M6-a,Neuronal membrane glycoprotein M6-a,,GPM6A抗体 |
| Swissprot | P51674 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human GPM6A |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:200; |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene.Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells.Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation.GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways.May be involved in neuronal NGF-dependent Ca2+ influx.May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. |
Images
Western Blot analysis of Human fetal brain tissue using GPM6A Polyclonal Antibody at dilution of 1:1050
Immunohistochemistry of paraffin-embedded Human brain using GPM6A Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer using GPM6A Polyclonal Antibody at dilution of 1:50
