GPNMB Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40473
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Glycoprotein nmb, Glycoprotein nmb like protein, Gpnmb, HGFIN, NMB, Osteoactivin, Transmembrane glycoprotein, Transmembrane glycoprotein HGFIN, Transmembrane glycoprotein NMB,,GPNMB抗体 |
| Swissprot | Q14956 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human Transmembrane glycoprotein NMB protein |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane, Endosome |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. |
