GPSM2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19960
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | DFNB82,G protein signalling modulator 2 (AGS3 like C. elegans),G protein signalling modulator 2,G-protein-signaling modulator 2,Gpsm2,GPSM2,HGNC:29501,LGN,LGN protein,Mosaic protein LGN,Pins,GPSM2抗体 |
Swissprot | P81274 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human GPSM2 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:30-1:150 |
Concentration | 1.92mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. Cytoplasm>cell cortex. Localizes in the cytoplasm in the interphase and at cell periphery in the metaphase. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses.The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange.This protein may play a role in neuroblast division and in the development of normal hearing.Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82).Alternative splicing results in multiple transcript variants. |