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GPSM2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19960

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms DFNB82,G protein signalling modulator 2 (AGS3 like C. elegans),G protein signalling modulator 2,G-protein-signaling modulator 2,Gpsm2,GPSM2,HGNC:29501,LGN,LGN protein,Mosaic protein LGN,Pins,GPSM2抗体
    Swissprot P81274
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Synthetic peptide of human GPSM2
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:30-1:150
    Concentration 1.92mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm. Cytoplasm>cell cortex. Localizes in the cytoplasm in the interphase and at cell periphery in the metaphase.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses.The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange.This protein may play a role in neuroblast division and in the development of normal hearing.Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82).Alternative splicing results in multiple transcript variants.
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