GPT Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16144
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | AAT1,Alanine aminotransferase 1,Alanine aminotransferase,ALAT1,ALT1,Glutamate pyruvate transaminase 1,Glutamic alanine transaminase 1,Glutamic pyruvate transaminase (alanine aminotransferase),Glutamic pyruvic transaminase 1,Glutamic--alanine transaminase 1,Glutamic--pyruvic transaminase 1,GPT 1,gpt,GPT1,GPT抗体 |
| Swissprot | P24298 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human GPT |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:25-1:100 |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. |
| Tissue specificity | Liver, kidney, heart, and skeletal muscles. Expressed at moderate levels in the adipose tissue. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase. |
