GRIA4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53406
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | AMPA 4,AMPA selective glutamate receptor 4,AMPA-selective glutamate receptor 4,AMPA4,GluA 4,GluA4,GluR 4,GluR D,GluR-4,GluR-D,GluR4,GLUR4C,GLURD,Glutamate receptor 4,Glutamate receptor ionotrophic AMPA 4,Glutamate receptor ionotropic,GRIA 4,Gria4,GRIA4,GRIA4抗体 |
| Swissprot | P48058 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human GRIA4 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.8mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Cell junction>synapse>postsynaptic cell membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. |
