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GRIK3 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19967

宿主: Rabbit

反应性: H,M,R

应用: WB

  • 详情
  • Overview

    Synonyms EAA5,Excitatory amino acid receptor 5,GLR 7,GLR7,GLU R7,GLUR 7,GluR 7a,GluR-7,GluR7,GluR7a,Glutamate receptor 7,Glutamate receptor,Glutamate receptor ionotropic kainate 3,GRIK 3,GRIK3,GRIK3,ionotropic kainate 3,GRIK3抗体
    Swissprot Q13003
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human GRIK3
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:2000;
    Concentration 1.5mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane. Cell junction>synapse>postsynaptic cell membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
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