GRIK3 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19967
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
Synonyms | EAA5,Excitatory amino acid receptor 5,GLR 7,GLR7,GLU R7,GLUR 7,GluR 7a,GluR-7,GluR7,GluR7a,Glutamate receptor 7,Glutamate receptor,Glutamate receptor ionotropic kainate 3,GRIK 3,GRIK3,GRIK3,ionotropic kainate 3,GRIK3抗体 |
Swissprot | Q13003 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human GRIK3 |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:500-1:2000; |
Concentration | 1.5mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. Cell junction>synapse>postsynaptic cell membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. |