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GRIN1 Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3300

货号:E-AB-70244

宿主: Rabbit

反应性: M

应用: IHC

  • 详情
  • Overview

    Synonyms GluN1,Glutamate [NMDA] receptor subunit zeta-1,Glutamate receptor ionotropic N methyl D aspartate 1,Glutamate receptor ionotropic,N-methyl-D aspartate,subunit 1,glutamate receptor ionotropic,NMDA 1,Grin1,MRD8,N methyl D aspartate receptor,N methyl D aspartate receptor channel subunit zeta 1,N methyl D aspartate receptor subunit NR1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1,NMDA 1,NMDA R1,NMDA receptor 1,NMDA1,NMDAR,NMDZ1,NR1,GRIN1抗体
    Swissprot P35438
    Source Rabbit
    Reactivity Mouse
    Immunogen KLH conjugated Synthetic peptide corresponding to Mouse NMDAR1
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:100-1:500
    Concentration 480 μg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, Synapse
    Tissue specificity Detected in brain (at protein level). Detected in brain.Highest expression level in CA1 field of hippocampus.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
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