GRIN1 Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3300 |
货号:E-AB-70244
宿主: Rabbit
反应性: M
应用: IHC
Overview
Synonyms | GluN1,Glutamate [NMDA] receptor subunit zeta-1,Glutamate receptor ionotropic N methyl D aspartate 1,Glutamate receptor ionotropic,N-methyl-D aspartate,subunit 1,glutamate receptor ionotropic,NMDA 1,Grin1,MRD8,N methyl D aspartate receptor,N methyl D aspartate receptor channel subunit zeta 1,N methyl D aspartate receptor subunit NR1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1,NMDA 1,NMDA R1,NMDA receptor 1,NMDA1,NMDAR,NMDZ1,NR1,GRIN1抗体 |
Swissprot | P35438 |
Source | Rabbit |
Reactivity | Mouse |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse NMDAR1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:100-1:500 |
Concentration | 480 μg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, Synapse |
Tissue specificity | Detected in brain (at protein level). Detected in brain.Highest expression level in CA1 field of hippocampus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Background | The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. |