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GRIN2B Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3300

货号:E-AB-70263

宿主: Rabbit

反应性: M,R

应用: IHC

  • 详情
  • Overview

    Synonyms AW490526,EIEE27,Glutamate [NMDA] receptor subunit epsilon 2,Glutamate [NMDA] receptor subunit epsilon-2,Glutamate Receptor Ionotropic N Methyl D Aspartate 2B,Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B,Glutamate receptor ionotropic NMDA2B,Glutamate receptor subunit epsilon 2,Glutamate receptor,ionotropic,NMDA2B (epsilon 2),GRIN 2B,GRIN2B,hNR 3,hNR3,MGC142178,MGC142180,MRD6,N methyl D asparate receptor channel subunit epsilon 2,N methyl D aspartate receptor subtype 2B,N methyl D aspartate receptor subunit 2B,N methyl D aspartate receptor subunit 3,N-methyl D-aspartate receptor subtype 2B,N-methyl-D-aspartate receptor subunit 3,NMDA NR2B,NMDA R2B,NMDAR2B,NMDE2,NMDE2,NME2,NR2B,NR3,GRIN2B抗体
    Swissprot Q01097,Q00960
    Source Rabbit
    Reactivity Mouse,Rat
    Immunogen Recombinant protein corresponding to Mouse NMDAR2B
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:200-1:800
    Concentration 170 μg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane. Cell junction>synapse>postsynaptic cell membrane.
    Tissue specificity Detected in brain (at protein level) (PubMed:8789948). Detected throughout the brain, and in brain stem trigeminal nucleus (PubMed:8789948). Detected in forebrain (PubMed:1377365).
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors.NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning.NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B).The NR2 subunit acts as the agonist binding site for glutamate.This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
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