GRIN2C Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15808
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | GluN2C,Glutamate [NMDA] receptor subunit epsilon-3,Glutamate Receptor Ionotropic N Methyl D Aspartate 2C,Glutamate receptor ionotropic,NMDA 2C,Glutamate receptor,ionotropic,N methyl D aspartate 2C,Grin2c,N Methly D Aspartate Receptor Channel Subunit Epsilon 3,N Methyl D Aspartate Receptor Subtype 2C,N methyl D aspartate receptor subunit 2C,N-methyl D-aspartate receptor subtype 2C,NMDAR2C,NMDE3,NR2C,OTTHUMP00000041930,GRIN2C抗体 |
| Swissprot | Q14957 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human GRIN2C |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Cell junction, synapse, postsynaptic cell membrane. |
| Tissue specificity | Mainly expressed in brain with predominant expression is in the cerebellum, also present in the hippocampus, amygdala, caudate nucleus, corpus callosum, subthalamic nuclei and thalamus. Detected in the heart, skeletal muscle and pancreas. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). |
