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gsta1 Polyclonal Antibody(Capture/Detector)

规格: / 25μg / 100μg
价格: / ¥800 / ¥2100

货号:AN000610P

货期:咨询

宿主: Rabbit

反应性: H

应用: ELISA Capture/Detector

  • 详情
  • Overview

    Synonyms GSTA1;GST2;GSTA1-1;GTH1;
    Swissprot P08263
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant Human gsta1 protein expressed by E.coli
    Application ELISA Capture/Detector
    Recommended dilution ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Isotype IgG
    Purification Antigen Affinity Purification
    Conjugation Unconjugated
    Storage instructions Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
    Storage buffer Sterile PBS,pH 7.4
    Background GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs,GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adenocarcinoma (Caco-2) cells in culture undergo spontaneous differentiation into mature enterocytes in association with progressive increases in expression of glutathione S-transferase alpha-1 (GSTA1). GSTA1 levels may play a role in modulating enterocyte proliferation but do not influence differentiation or apoptosis. GSTA1 may play a key role during pregnancy.
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