H2AFJ Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19114
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | H2A Histone Family Member J,Histone H2A.J,H2a/J,H2AFJ抗体 |
| Swissprot | Q9BTM1 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human H2AFJ |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:200-1:300; |
| Concentration | 1.14mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Chromosome, Nucleosome core, Nucleus |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is located on chromosome 12 and encodes a replication-independent histone that is a variant H2A histone. The protein is divergent at the C-terminus compared to the consensus H2A histone family member. This gene also encodes an antimicrobial peptide with antibacterial and antifungal activity. |
Images
Western blot analysis of Jurkat cell lysate using H2AFJ Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using H2AFJ Polyclonal Antibody at dilution of 1:170(×200)
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using H2AFJ Polyclonal Antibody at dilution of 1:170(×200)
