HBG1/HBG2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18774
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | A gamma globin,G gamma globin,Gamma 1 globin,Gamma 2 globin,Gamma A hemoglobin,Gamma globin,Hb F Agamma,Hb F Ggamma,hbfagamma,hbfggamma,HBG 1,HBG 2,HBG1,HBG2,HBGA,HBGR,Hemoglobin gamma 1 chain ,Hemoglobin gamma 2 chain ,Hemoglobin gamma A,Hemoglobin gamma A chain ,Hemoglobin gamma G,Hemoglobin gamma G chain ,Hemoglobin gamma regulator of,Hemoglobin subunit gamma 1,Hemoglobin subunit gamma 2,HSGGL 1,HSGGL1,Methemoglobin,PRO 2979,PRO2979,HBG1/HBG2抗体 |
| Swissprot | P69891,P69892 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human HBG1/HBG2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:40-1:200; |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasmic |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. |
