HDAC2 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70243
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | D10Wsu179e,HD 2,HD2,HDAC 2,Hdac2,HDAC2,Histone deacetylase 2 (HD2),Histone deacetylase 2,OTTHUMP00000017046,OTTHUMP00000227077,OTTHUMP00000227078,RPD3,transcriptional regulator homolog RPD3,YAF1,YY1 associated factor 1,YY1 transcription factor binding protein,Yy1bp,HDAC2抗体 |
| Swissprot | P70288,Q92769 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse HDAC2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:300-1:1000 |
| Concentration | 1.8 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Tissue specificity | Widely expressed; lower levels in brain and lung.Highest expression level in cerebral cortex. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. |
Images
Immunohistochemistry analysis of paraffin-embedded human lung cancer using HDAC2 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded mouse liver using HDAC2 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded Rat kidney using HDAC2 Polyclonal Antibody at dilution of 1:1000.
