HES1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70255
宿主: Rabbit
反应性: M,R
应用: WB
Overview
| Synonyms | bHLHb39,C-HAIRY1,c-hairy1A,Class B basic helix-loop-helix protein 39,FLJ20408,Hairy and enhancer of split 1 (Drosophila),Hairy and enhancer of split 1,Hairy homolog (Drosophila),Hairy homolog,Hairy like,Hairy-like protein,HAIRY1,HES-1,hes1,Hes1 hairy and enhancer of split 1 (Drosophila),HES1,HHL,HL,HRY,MGC129109,OTTHUMP00000209031,RHL,Transcription factor HES-1,HES1抗体 |
| Swissprot | P35428 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse HES1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 410 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus |
| Tissue specificity | Expressed at high levels in undifferentiated neural precursor cells, but the level of expression decreases as neural differentiation proceeds.Highest expression level in urinary bladder urothelium. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. |
客户发表文献
- 文献: Modification of α2,6‐sialylation mediates the invasiveness and tumorigenicity of non‐small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway
样品类型: Cell - 文献: ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway
样品类型: Cell sample(Cervical carcinoma cell lines SiHa and HeLa
