HGF Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14122
宿主: Rabbit
反应性: H,M,R
应用: IHC,ELISA
Overview
| Synonyms | DFNB39,F TCF,Fibroblast derived tumor cytotoxic factor,Hepatocyte growth factor (hepapoietin A,scatter factor),Hepatocyte growth factor,Hepatocyte growth factor beta chain,Hepatocyte growth factor precursor,Hepatopoietin A,Hepatopoietin-A,Hgf,HGF,HGFB,HPTA,Lung fibroblast derived mitogen,OTTHUMP00000161349,OTTHUMP00000206710,OTTHUMP00000206711,OTTHUMP00000206712,OTTHUMP00000206713,OTTHUMP00000206730,Scatter factor,SF,HGF抗体 |
| Swissprot | P14210 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human HGF |
| Application | IHC(Detection kit: E-IR-R213),ELISA |
| Recommended dilution | IHC,,1:50-1:200; |
| Concentration | 0.8 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Extracellular region or secreted,extracellular region,extracellular space,Other locations:membrane,platelet alpha granule lumen |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. |
