HINT2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14123
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | 1190005L05Rik,HINT-2,HINT-3,HINT2,HINT2,histidine triad nucleotide binding protein 2,Histidine triad nucleotide-binding protein 2,HIT-17,HIT-17kDa,mitochondrial,PKCI-1-related HIT protein,Protein kinase C inhibitor 2,HINT2抗体 |
| Swissprot | Q9BX68 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human HINT2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 0.8 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion. |
| Tissue specificity | High expression in liver and pancreas. Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Hint2 (histidine triad nucleotide binding protein 2), also known as HIT-17, is a 163 amino acid secreted protein that contains one HIT domain, a histidine triad that has catalytic activity toward the -phosphate of ribonucleotides.Via its HIT domain, Hint2 is thought to function as a hydrolase that is encoded by a gene whicHuman, Mouseaps to chromosome 9.Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes.Hereditary hemorrhagic telangiectasia and Familial dysautonomia are both associated with chromosome 9.Notably, chromosome 9 encompasses the largest interferon family gene cluster. |
Images
Western Blot analysis of Mouse heart and Human hepatocellular carcinoma tissue using HINT2 Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human breast cancer using HINT2 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer using HINT2 Polyclonal Antibody at dilution of 1:50
