HIST1H2BA Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19784
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | HIST1H2BA,testis,bA317E16.3,H2B,H2B histone family member U,H2B histone family member U testis specific,H2B histone family,member U,(testis specific),H2B testis,H2B1A,H2BFU,H2BT,HIST1H2BA,Histone 1,H2ba,Histone cluster 1 H2ba,Histone H2B,Histone H2B testis,Histone H2B type 1 A,Histone H2B type 1-A,Histone H2B type 1A,STBP,Testis specific histone H2B,Testis-specific histone H2B,TSH 2B,TSH2B,TSH2B.1,HIST1H2BA抗体 |
| Swissprot | Q96A08 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human HIST1H2BA |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:300; |
| Concentration | 1.98mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Chromosome. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination , acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts . |
Images
Western blot analysis of Human prostate tissue PC-3 A549 and TM4 cell lysates using HIST1H2BA Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using HIST1H2BA Polyclonal Antibody at dilution of 1:45(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using HIST1H2BA Polyclonal Antibody at dilution of 1:45(×200)
