Histone H2A.X Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70233
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | H2A histone family member X,H2A histone family member X,H2A.FX,H2A.X,H2a/x,H2AFX,H2AX,H2AX,Histone H2A.X,Histone H2A.X抗体 |
| Swissprot | P16104,P27661 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Histone H2A.X |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:300-1:800; |
| Concentration | 0.86 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Chromosome, Nucleosome core, Nucleus |
| Tissue specificity | Highest expression level in embryo |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. |
Images
Western Blot analysis of various samples using Histone H2A.X Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded mouse testis using Histone H2A.X Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded rat testis using Histone H2A.X Polyclonal Antibody at dilution of 1:400.
