Histone H2B Monoclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥580 / ￥1420 / ￥2310 |
货号：E-AB-22086
宿主: Mouse
反应性: H,M,R
应用: WB,IF
Overview
| Synonyms | HIST1H2BA,testis,bA317E16.3,H2B,H2B histone family member U,H2B histone family member U testis specific,H2B histone family,member U,(testis specific),H2B testis,H2B1A,H2BFU,H2BT,HIST1H2BA,Histone 1,H2ba,Histone cluster 1 H2ba,Histone H2B,Histone H2B testis,Histone H2B type 1 A,Histone H2B type 1-A,Histone H2B type 1A,STBP,Testis specific histone H2B,Testis-specific histone H2B,TSH 2B,TSH2B,TSH2B.1,Histone H2B抗体 |
| Swissprot | P33778 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic Peptide |
| Application | WB(Detection kit: E-IR-R304),IF |
| Recommended dilution | WB,,1:1000-3000;IF,,1:100-200; |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Cellular localization | Cytosol,Nucleus,nuclear chromosome, telomeric region,nucleoplasm,nucleus,Other locations:nucleosome |
| Clone No | Clone:3C3 |
|---|---|
| Isotype | IgG |
| Purification | Protein A purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.4 |
| Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. HIST1H2BB (Histone Cluster 1 H2B Family Member B) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BN. |
