HK1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14707
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | BB404130,Brain form hexokinase,dea,DrHXK1,EC 2.7.1.1,Glycolytic enzyme,HEXOKIN,hexokinase I,Hexokinase PI,Hexokinase type I,Hexokinase,tumor isozyme,Hexokinase-1,Hexokinase-A,HK I,HK1,HK1 tb,Hk1-s,HK1-ta,HK1-tb,HK1-tc,HKD,HKI,HMSNR,HXK1,HXK1,im:7148527,mHk1-s,wu:fc09d08,wu:fc16e02,wu:fc21e02,wu:fq14b11,zgc:55790,zgc:77618,HK1抗体 |
| Swissprot | P19367 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human HK1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion outer membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding. |
| Tissue specificity | Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. |
