HLA-E Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18997
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | HLA class I histocompatibility antigen E alpha chain,EA1.2,EA2.1,HLA 6.2,HLA class I histocompatibility antigen alpha chain E,HLA class I histocompatibility antigen E alpha chain precursor ,HLA class I histocompatibility antigen E alpha chain precursor,HLA6.2,HLAE,Lymphocyte antigen,Major histocompatibility complex class I E,MHC,MHC class I antigen E,MHC HLA E alpha 1,MHC HLA E alpha 2.1,QA1,HLA-E抗体 |
| Swissprot | P13747 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human HLA-E |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:300 |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane; Single-pass type I membrane protein |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. |
