HLA-G Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18031
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | B2 microglobulin,DADB-15K14.8,HLA 6.0,HLA class I histocompatibility antigen alpha chain G,HLA class I histocompatibility antigen,alpha chain G,HLA class I molecule,HLA G,HLA G antigen,HLA G histocompatibility antigen class I G,HLA G3,HLA-G,HLA-G histocompatibility antigen,class I,HLA60,HLAG,HLAG,Major histocompatibility complex class I G,MHC class I antigen,MHC class I antigen G,MHC G,T-cell A locus,TCA,HLA-G抗体 |
| Swissprot | P17693 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human HLA-G |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:300 |
| Concentration | 1.26mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Human major histocompatibility complex (MHC) antigens,also referred to as human leukocyte antigens (HLA),are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface,where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance. |
