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HMGB2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-12506

宿主: Rabbit

反应性: H,M,R

应用: WB

  • 详情
  • Overview

    Synonyms C80539,High mobility group (nonhistone chromosomal) protein 2,High mobility group box 2,High mobility group protein 2,High mobility group protein B2,HMG 2,HMG B2,HMG-2,HMG2,HMGB2,HMGB2,HMGB2抗体
    Swissprot P26583
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human HMGB2
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:2000-1:5000;
    Concentration 0.9 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus. Chromosome.
    Tissue specificity Expressed in gastric and intestinal tissues (at protein level).
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
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