HNF1A Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19305
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Albumin proximal factor,Hepatic nuclear factor 1 alpha,Hepatic nuclear factor 1,Hepatic transcription factor 1 alpha,Hepatic transcription factor 1,Hepatocyte nuclear factor 1-alpha,HNF 1,HNF 1A,HNF-1-alpha,HNF-1A,hnf1a,HNF1A,Interferon production regulator factor,LF B1,LF B1 hepatic nuclear factor,LFB 1,LFB1,LFB1 hepatic nuclear factor,Liver specific transcription factor LF B1,Liver specific transcription factor LFB1,Liver-specific transcription factor LF-B1,Maturity onset diabetes of the young 3,MODY 3,MODY3,TCF 1,TCF-1,TCF1,Transcription factor 1,Transcription factor 1 hepatic,HNF1A抗体 |
| Swissprot | P20823 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human HNF1A |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:300 |
| Concentration | 2.46mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. |
