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HNF1B Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-12661

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • 文献(1)
  • Overview

    Synonyms FJHN,Hepatocyte nuclear factor 1 beta,Hepatocyte nuclear factor 1-beta,HNF 1B,HNF 2,HNF-1-beta,HNF-1B,HNF1 beta,HNF1 homeobox B,HNF1B,HNF1B,HNF1beta,HNF2,Homeoprotein LF B3,Homeoprotein LFB3,HPC11,LF B3,LFB3,MODY 5,MODY5,TCF 2,TCF 2 protein,TCF-2,TCF2,TCF2 protein,Transcription factor 2,Transcription factor 2 hepatic,Variant hepatic nuclear factor 1,Variant hepatic nuclear factor,VHNF 1,vHNF1,HNF1B抗体
    Swissprot P35680
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human HNF1B
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:100-1:300
    Concentration 0.9 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
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