HNF1B Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-12661
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | FJHN,Hepatocyte nuclear factor 1 beta,Hepatocyte nuclear factor 1-beta,HNF 1B,HNF 2,HNF-1-beta,HNF-1B,HNF1 beta,HNF1 homeobox B,HNF1B,HNF1B,HNF1beta,HNF2,Homeoprotein LF B3,Homeoprotein LFB3,HPC11,LF B3,LFB3,MODY 5,MODY5,TCF 2,TCF 2 protein,TCF-2,TCF2,TCF2 protein,Transcription factor 2,Transcription factor 2 hepatic,Variant hepatic nuclear factor 1,Variant hepatic nuclear factor,VHNF 1,vHNF1,HNF1B抗体 |
Swissprot | P35680 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human HNF1B |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:100-1:300 |
Concentration | 0.9 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. |