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HNRNPH2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-52276

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC

  • 详情
  • Overview

    Synonyms FTP 3,FTP-3,FTP3,Heterogeneous nuclear ribonucleoprotein H'',heterogeneous nuclear ribonucleoprotein H2 (H'),Heterogeneous nuclear ribonucleoprotein H2,HNRH2,hnRNP H'',hnRNP H2,hnRNPH',HNRNPH2,HNRPH',HNRPH2,HNRNPH2抗体
    Swissprot P55795
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Fusion protein of human HNRNPH2
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:30-1:150;
    Concentration 0.5mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus>nucleoplasm.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA).These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport.While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm.The hnRNP proteins have distinct nucleic acid binding properties.The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs.It is very similar to the family member HNRPH1.This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype.Alternative splicing results in multiple transcript variants encoding the same protein.Read-through transcription between this locus and the ribosomal protein L36a gene has been observed.
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