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HOXD8 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19416

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms Homeo Box D8,HOX4E,Homeobox Protein 5.4,Homeo Box 4E,HOX5.4,HOX4,,HOXD8抗体
    Swissprot P13378
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Synthetic peptide of human HOXD8
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:30-1:150
    Concentration 1.6mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.
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