HOXD8 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19416
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | Homeo Box D8,HOX4E,Homeobox Protein 5.4,Homeo Box 4E,HOX5.4,HOX4,,HOXD8抗体 |
Swissprot | P13378 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human HOXD8 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:30-1:150 |
Concentration | 1.6mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants. |