HRG Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16488
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | DKFZp779H1622,Histidine proline rich glycoprotein,Histidine rich glycoprotein,HPRG,HRGP,Thrombophilia due to elevated HRG,HRG抗体 |
| Swissprot | P04196 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human HRG |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 1.1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted |
| Tissue specificity | Expressed in macrophages and in malignant cells. Expressed by the liver and secreted in plasma (at protein level). |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. |
